Orthopedics

Spine
Spine
Orthopedics
Orthopedics
Cardiovascular
Cardiovascular
Otorhino – laryngology
Otorhino – laryngology
Neurology
Neurology
Thoraco – abdominal
Thoraco – abdominal
Group 2096

The MMI Advantage

Group 2049
100+ unique orthopedic treatments evaluated

MMI’s breadth of experience ranges from soft tissue repair and regeneration to hemi and total joint replacements.

Validated and accurate JSW/ JSN measurement technique
Validated and accurate JSW/ JSN measurement technique

Our joint space narrowing measurement technique has been validated for both accuracy and  reproducibility using our patented QMA® technology.

Experienced with all major joints in the body
Experienced with all major joints in the body

We have evaluated all of the major articular joints in the body, including in the hands and feet.

Experience and Expertise

MMI has over fifteen years of experience in providing core lab support for more than 150 orthopedic device and biopharmaceutical companies internationally, including 14 of the top 15 global market leaders.

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Modality Expertise

X-ray
MRI
CT
Ultrasound

At MMI, we have evaluated well over 100 unique treatments for musculoskeletal disorders of the hip, knee, ankle, wrist, shoulder, elbow, peripheral joints, and long bones involving osteoarthritis, rheumatoid arthritis, trauma, and sports medicine. Broadly, our musculoskeletal treatment experience includes but is not limited to drugs, stem cells, biologics, viscosupplements, marrow stimulation, tissue grafting, ablation, bone fillers, fixation devices, bioresorbable scaffolds, biphasic implants, biomimetic devices, resurfacing, and partial and total arthroplasty.

We are experienced in virtually all major quantitative and semi-quantitative scoring systems to assess disease severity and response to therapy from medical imaging. When appropriate, we apply validated, computer-assisted methods to objectively document the effect of new treatments. We offer a variety of validated tools and techniques to facilitate these evaluations. Our proprietary and patented technology, QMA®, offers unique quantitation and visualization capabilities that improve the reliability of common assessments, including change in joint space width and alignment; implant migration, subsidence, and rotation; progressive bone/implant interface remodeling; and fracture reduction, stabilization, and healing. Learn more here.

WHAT WE OFFER

Analysis Capabilities

Tissue structure, morphometry, and hydration (e.g. thickness, volume, lesion depth, T2 and T1ρ relaxation mapping)

Soft tissue repair & regeneration (cartilage, meniscus, tendon, ligament)

Joint space width and narrowing

Joint stability and alignment

Whole joint health semi-quantitative scoring systems

Implant stability, fixation, and alignment

Bone-implant and cement-implant interface remodeling

Structural bony anatomy (e.g. osteophytes, cysts, HO)

Fracture reduction, stabilization, and healing

JSW measurement 2
Radiographic joint space width using the mid-coronal plane measurement method
cartilage-map
MR relaxation mapping of knee cartilage
Preoperative rotator cuff tear length on sagittal MR
Preoperative rotator cuff tear length on sagittal MR
Femoral bone density analysis from CT
Femoral bone density analysis from CT
MTP fusion
Successful fusion of the MTP at 24 months
3D surface of cartilage created from an MRI
3D surface of cartilage created from an MRI
Tibial-Cartilage-Thickness-Map
Tibial cartilage thickness mapping
Cup inclination
Acetabular cup inclination and obturator-tear drop distance measurements to assess coverage and pelvic positioning, respectively

Some of Our Experts

Timothy Mosher, MD

Kenneth L. Chair, Department of Radiology and Distinguished Professor of Radiology and Orthopaedic Surgery at Penn State University 

Dr. Mosher is a clinical musculoskeletal radiologist with a research interest in osteoarthritis. He is a fellow of the International Society for Magnetic Resonance in Medicine (ISMRM) and has served on numerous NIH scientific review groups, the Scientific Advisory Board for the Canadian Arthritis Network, the Canadian Foundation for Innovation, and as an industry consultant in the areas of imaging applications to musculoskeletal projects.  Dr. Mosher has published over 80 books and manuscripts with the majority in the area of musculoskeletal imaging, quantitative cartilage imaging, and MRI technical development.

William Morrison, MD FACR

Professor of Radiology and Director of Musculoskeletal Radiology at Thomas Jefferson University Hospital

Dr. Morrison is an internationally recognized authority in musculoskeletal imaging with over 30 years’ experience. He has co-authored or edited 13 textbooks including Problem Solving in Musculoskeletal Radiology and Imaging of the Musculoskeletal System, and published 100 book chapters and over 150 peer-reviewed articles. Dr. Morrison has served on the editorial board of the journals Radiology, Skeletal Radiology, and Seminars in Musculoskeletal Radiology. He has served on Expert Panels for the American College of Radiology (ACR), the American Board of Radiology (ABR), and the American Diabetes Association (ADA). He is also a past president of the Society of Skeletal Radiology (SSR).

Let MMI provide insights into your clinical study imaging.

Have questions? We’ll connect you immediately to one of our scientific managers and imaging experts. Your time is precious, and we want to make the most out of it.

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