Leading Core Lab for Spine Trials
MMI has provided imaging core lab services for FDA-regulated studies of the spine since 2000. Images from over three quarters of all US spine IDE trials are managed through our facility. Our readers have extensive experience with image-based assessments of fusion, arthroplasty, and disc repair. Our proprietary, 510(k)-cleared, Quantitative Motion Analysis software (QMA®) has the highest accuracy and reproducibility of any published method for spine image analysis. Additionally, our scientific experts have assisted with the interpretation of outcomes from numerous clinical studies. No other core lab offers our unique combination of experienced readers, scientific expertise, and specialized technology for spine clinical trials.
Experience and Expertise
We have extensive experience with motion preserving technology, including total disc replacement and dynamic stabilization. Our spine fusion experience includes assessments of allografts, autografts, and bone graft substitutes. We are leaders in the evaluation of stem cells and biologics for tissue repair and regeneration. We also routinely evaluate treatments for fracture, trauma, and deformity.
A summary of our treatment experience is provided below.
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We offer unique clinical expertise, awareness of the latest advances in spine imaging, and an understanding of current regulatory requirements and trends. Our Faculty Directors for spine trials include:
John Hipp, PhD
- Over 25 years' experience in quantitative imaging methods for spine research
- Recipient of the prestigious AAOS Kappa Delta Orthopedic Research Award
- Former Director of the Spine Research Lab at Baylor College of Medicine
- Published over 90 imaging-related papers and book chapters
- Managed development of more than 50 spine-related imaging charters
- Reviewer for eight leading journals including Spine and The Spine Journal
Alan Williams, MD
- Fellowship-trained neuroradiologist with over 30 years' clinical experience, including 17 years as a Neuroradiology Section Chief
- Former President of the American Society of Spine Radiology
- Published over 90 peer-reviewed papers and 10 book chapters
- Invited speaker at many national and international meetings
- Serves in editorial capacity at the American Journal of Neuroradiology and Radiology